|
|
nicotinamide + H2O <=> NH3 + nicotinate
|
3.5.1.13
aryl-acylamidase
3.5.1.19
nicotinamidase
3.5.1.4
amidase
|
–
–
–
|
BMK
|
|
BRENDA:
BR26099
KEGG:
R01268
MetaCyc:
NICOTINAMID-RXN
|
|
|
|
nicotinate + O2 + NADPH <=> 2-(Hydroxymethyl)-3-(acetamidomethylene)succinate + NADP+
|
1.14.13.241
5-pyridoxate monooxygenase
|
–
|
K
|
|
BRENDA:
BR40441
KEGG:
R04570
MetaCyc:
5-PYRIDOXATE-DIOXYGENASE-RXN
|
|
|
|
S-adenosyl-L-methionine + nicotinate <=> S-adenosyl-L-homocysteine + Trigonelline
|
2.1.1.7
nicotinate N-methyltransferase
|
–
|
MK
|
|
BRENDA:
BR40553
KEGG:
R01721
MetaCyc:
NICOTINATE-N-METHYLTRANSFERASE-RXN
|
|
|
|
nicotinic_acid_mononucleotide + 5,6-Dimethylbenzimidazole <=> alpha-ribazole_5''-phosphate + nicotinate + H+
|
2.4.2.21
nicotinate-nucleotide---dimethylbenzimidazole phosphoribosyltransferase
2.4.2.55
nicotinate D-ribonucleotide:phenol phospho-D-ribosyltransferase
|
–
–
|
BMK
|
|
BRENDA:
BR44272
KEGG:
R04148
MetaCyc:
DMBPPRIBOSYLTRANS-RXN
SABIO-RK:
3868
|
|
|
|
nicotinate + 5-phospho-alpha-D-ribose_1-diphosphate + ATP + H2O <=> nicotinic_acid_mononucleotide + diphosphate + ADP + phosphate
|
6.3.4.21
nicotinate phosphoribosyltransferase
|
–
|
BMK
|
|
BRENDA:
BR47484
KEGG:
R01724
MetaCyc:
NICOTINATEPRIBOSYLTRANS-RXN
|
|
|
|
UDP-glucose + nicotinate <=> N-glucosylnicotinate + UDP
|
2.4.1.196
nicotinate glucosyltransferase
|
–
|
M
|
|
BRENDA:
BR47492
KEGG:
R01722
MetaCyc:
NICOTINATE-GLUCOSYLTRANSFERASE-RXN
|
|
|
|
nicotinate + H2O + NADP+ <=> 6-Hydroxynicotinate + NADPH + H+
|
1.17.1.5
nicotinate dehydrogenase
|
–
|
MK
|
|
BRENDA:
BR48018
KEGG:
R01720
MetaCyc:
RXN-7637
|
|
|
|
nicotinate + H2O + Ferrocytochrome <=> 6-Hydroxynicotinate + Ferrocytochrome + H+
|
1.17.2.1
nicotinate dehydrogenase (cytochrome)
|
–
|
MK
|
|
BRENDA:
BR49237
KEGG:
R09473
MetaCyc:
NICOTINATE-DEHYDROGENASE-RXN
|
|
|
|
nicotinic_acid_mononucleotide + phenol <=> nicotinate + phenyl_5-phospho-alpha-D-ribofuranoside + H+
|
2.4.2.21
nicotinate-nucleotide---dimethylbenzimidazole phosphoribosyltransferase
2.4.2.55
nicotinate D-ribonucleotide:phenol phospho-D-ribosyltransferase
|
–
–
|
M
|
|
BRENDA:
BR50667
KEGG:
R10608
MetaCyc:
RXN-14701
|
|
|
|
NADP+ + nicotinate <=> nicotinate-adenine_dinucleotide_phosphate + nicotinamide
|
2.4.99.20
2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase
3.2.2.5
NAD+ glycohydrolase
|
–
–
|
K
|
|
BRENDA:
BR50955
KEGG:
R00119
MetaCyc:
RXN-13973
SABIO-RK:
7319
|
|
|
|
2''-phospho-cyclic_ADP-ribose + nicotinate <=> nicotinate-adenine_dinucleotide_phosphate
|
2.4.99.20
2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase
|
–
|
|
|
BRENDA:
BR50957
KEGG:
R10632
MetaCyc:
RXN-13972
|
|
|
|
Isopyridoxal + NAD+ + H2O <=> nicotinate + NADH + H+
|
1.2.1.102
isopyridoxal dehydrogenase (5-pyridoxate-forming)
|
–
|
K
|
|
BRENDA:
BR52560
KEGG:
R12265
MetaCyc:
RXN-19620
|
|
|
|
nicotinic_acid_mononucleotide + H2O <=> D-ribose_5-phosphate + nicotinate + H+
|
3.2.2.14
NMN nucleosidase
3.2.2.M4
|
–
–
|
M
|
|
BRENDA:
BS115941
MetaCyc:
RXN-8444
|
|
|
|
nicotinate + H2O + acceptor <=> 6-Hydroxynicotinate + reduced_acceptor
|
1.17.99
1.3.99.18
quinaldate 4-oxidoreductase
1.5.99.4
nicotine dehydrogenase
|
–
–
–
|
M
|
|
BRENDA:
BS259398
MetaCyc:
RXN-11353
|
|
|
|
nicotinic_acid_mononucleotide + benzimidazole <=> 1-alpha-D-ribofuranosylbenzimidazole_5'-phosphate + nicotinate + H+
|
2.4.2.21
nicotinate-nucleotide---dimethylbenzimidazole phosphoribosyltransferase
|
–
|
M
|
|
BRENDA:
BS323212
MetaCyc:
RXN-19298
|
|
|
|
nicotinic_acid_mononucleotide + p-Cresol <=> nicotinate + 4-methylphenyl_5-phospho-alpha-D-ribofuranoside + H+
|
2.4.2.55
nicotinate D-ribonucleotide:phenol phospho-D-ribosyltransferase
|
–
|
M
|
|
BRENDA:
BS421917
MetaCyc:
RXN-16790
|
|
|
|
nicotinic_acid_mononucleotide + 5-methoxybenzimidazole <=> N1-(5-phospho-alpha-D-ribosyl)-5-methoxybenzimidazole + nicotinate + H+
|
2.4.2.21
nicotinate-nucleotide---dimethylbenzimidazole phosphoribosyltransferase
|
–
|
M
|
|
BRENDA:
BS435357
MetaCyc:
RXN-19300
|
|
|
|
nicotinic_acid_mononucleotide + 5-methylbenzimidazole <=> N1-(5-phospho-alpha-D-ribosyl)-5-methylbenzimidazole + nicotinate + H+
|
2.4.2.21
nicotinate-nucleotide---dimethylbenzimidazole phosphoribosyltransferase
|
–
|
M
|
|
BRENDA:
BS435358
MetaCyc:
RXN-19306
|
|
|
|
beta-D-ribosylnicotinate + H2O <=> nicotinate + D-ribose
|
3.2.2.3
uridine nucleosidase
|
–
|
K
|
|
BRENDA:
BS406115
KEGG:
R10046
|
|
|
|
Pyridine-3-aldehyde + NAD+ + H2O <=> nicotinate + NADH
|
1.2.1.19
aminobutyraldehyde dehydrogenase
1.2.1.28
benzaldehyde dehydrogenase (NAD+)
1.2.1.3
aldehyde dehydrogenase (NAD+)
|
–
–
–
|
|
|
BRENDA:
BS231542
SABIO-RK:
6891
|
|
|
|
nicotinate + glycine + ATP <=> Nicotinurate + AMP + diphosphate
|
not assigned
|
–
|
K
|
|
KEGG:
R01723
|
|
|
|
nicotinate <=> 2-Methyleneglutarate
|
not assigned
|
–
|
|
|
KEGG:
R01725
|
|
|
|
beta-D-ribosylnicotinate + phosphate <=> nicotinate + alpha-D-ribose_1-phosphate + H+
|
2.4.2.1
purine-nucleoside phosphorylase
|
–
|
K
|
|
KEGG:
R02295
|
|
|
|
Nicotine + CO2 + H+ <=> 1-Methylpyrrolinium + nicotinate
|
not assigned
|
–
|
K
|
|
KEGG:
R02861
|
|
|
|
anabasine + CO2 <=> DELTA1-piperideine + nicotinate
|
not assigned
|
–
|
K
|
|
KEGG:
R05128
|
|
|
|
nicotinate + 3,6-Dihydropyridine <=> Anatabine + CO2
|
not assigned
|
–
|
K
|
|
KEGG:
R06779
|
|
|
|
nicotinate <=> 3,6-Dihydronicotinic_acid
|
not assigned
|
–
|
K
|
|
KEGG:
R08426
|
|
|
|
H+ + nicotinate + NADPH <=> 3,6-Dihydronicotinate + NADP+
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-13057
|
|
|
|
nicotinic_acid_mononucleotide + adenine <=> nicotinate + adenine_ribotide_phosphate + H+
|
2.4.2.21
nicotinate-nucleotide---dimethylbenzimidazole phosphoribosyltransferase
|
–
|
M
|
|
MetaCyc:
RXN-19295
|
|
|
|
nicotinic_acid_mononucleotide + 5-hydroxybenzimidazole <=> 5-hydroxybenzimidazole_ribotide_phosphate + nicotinate + H+
|
2.4.2.21
nicotinate-nucleotide---dimethylbenzimidazole phosphoribosyltransferase
|
–
|
M
|
|
MetaCyc:
RXN-19299
|
|
|
|
nicotinic_acid_mononucleotide + 5-methoxy-6-methylbenzimidazole <=> 5-methoxy-6-methylbenzimidazole_ribotide_phosphate + nicotinate + H+
|
2.4.2.21
nicotinate-nucleotide---dimethylbenzimidazole phosphoribosyltransferase
|
–
|
M
|
|
MetaCyc:
RXN-19301
|
|
|
|
nicotinic_acid_mononucleotide + 2-methyladenine <=> nicotinate + 2-methyladenine_ribotide_phosphate + H+
|
2.4.2.21
nicotinate-nucleotide---dimethylbenzimidazole phosphoribosyltransferase
|
–
|
M
|
|
MetaCyc:
RXN-19316
|
|
|
|
H+ + nicotinate + D-ribulose_1-phosphate <=> beta-D-ribosylnicotinate + phosphate
|
2.4.2
|
–
|
M
|
|
MetaCyc:
RXN-8442
|
|
|
|
nicotinate + 5-phospho-alpha-D-ribose_1-diphosphate + ITP + H2O <=> nicotinic_acid_mononucleotide + diphosphate + IDP + phosphate
|
6.3.4.21
nicotinate phosphoribosyltransferase
|
–
|
|
|
BRENDA:
BS453771
|
|
|
|
3-Cyanopyridine + H2O <=> nicotinate + NH3
|
3.5.5.1
nitrilase
3.5.5.5
arylacetonitrilase
3.5.5.7
aliphatic nitrilase
|
–
–
–
|
|
|
BRENDA:
BS141122
|
|
|
|
nicotinate + H2O + 2,6-dichlorophenolindophenol <=> 6-Hydroxynicotinate + reduced_2,6-dichlorophenolindophenol
|
1.17.1.5
nicotinate dehydrogenase
|
–
|
|
|
BRENDA:
BS443796
|
|
|
|
Pyridine-3-aldehyde + H2O + 2,6-dichlorophenolindophenol <=> nicotinate + reduced_2,6-dichlorophenolindophenol
|
1.2.99.7
aldehyde dehydrogenase (FAD-independent)
|
–
|
|
|
BRENDA:
BS371888
|
|
|
|
S-adenosyl-L-methionine + nicotinate <=> S-adenosyl-L-homocysteine + nicotinic_acid_methyl_ester
|
2.1.1.B119
|
–
|
|
|
BRENDA:
BR53134
|
|
|
|
nicotinate + 5-phospho-alpha-D-ribose_1-diphosphate + GTP + H2O <=> nicotinic_acid_mononucleotide + diphosphate + GDP + phosphate
|
6.3.4.21
nicotinate phosphoribosyltransferase
|
–
|
|
|
BRENDA:
BS453772
|
|
|
|
nicotinate + NADH + O2 + H+ <=> 2-(acetamidomethylene)-beta-hydroxymethyl_succinate + NAD+
|
1.14.13.242
3-hydroxy-2-methylpyridine-5-carboxylate monooxygenase
|
–
|
|
|
BRENDA:
BS442220
|
|
|
|
nicotinate + NADH + H+ + O2 <=> alpha-(N-acetylaminomethylene)-beta-hydroxymethyl_succinic_acid + NAD+ + H2O
|
1.14.13.242
3-hydroxy-2-methylpyridine-5-carboxylate monooxygenase
|
–
|
|
|
BRENDA:
BS440944
|
|
|
|
nicotinate + H2O + NAD+ <=> 6-Hydroxynicotinate + NADH + H+
|
1.17.1.5
nicotinate dehydrogenase
|
–
|
|
|
BRENDA:
BS442495
|
|
|
|
3-carboxypyridine_N-oxide + reduced_benzyl_viologen + H2O <=> nicotinate + Oxidized_benzyl_viologen
|
1.8.5.3
respiratory dimethylsulfoxide reductase
|
–
|
|
|
BRENDA:
BS414023
|
|
|
|
thiamine + nicotinate <=> 4-methyl-5-(2-hydroxyethyl)-thiazole + 1-[(4-amino-2-methylpyrimidin-5-yl)methyl]-3-carboxypyridinium
|
2.5.1.2
thiamine pyridinylase
|
–
|
|
|
BRENDA:
BS353813
|
|
|
|
nicotinate + NADPH + O2 + H2O <=> 2-(acetylaminomethylene)succinate + NADP+ + H2O
|
1.14.13.241
5-pyridoxate monooxygenase
|
–
|
|
|
BRENDA:
BS288600
|
|
|
|
NADP+ + nicotinate <=> nicotinate-adenine_dinucleotide_phosphate
|
3.2.2.6
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase
|
–
|
|
|
BRENDA:
BS417395
|
|
|
|
ethyl_pyridine-3-carboxylate + H2O <=> nicotinate + ethanol
|
3.5.1.19
nicotinamidase
|
–
|
|
|
BRENDA:
BS433720
|
|
|
|
N5-nicotinyl-L-ornithine + H2O <=> L-ornithine + nicotinate
|
3.5.1.17
acyl-lysine deacylase
|
–
|
|
|
BRENDA:
BS116211
|
|
|
|
N6-nicotinyl-L-Lysine + H2O <=> L-lysine + nicotinate
|
3.5.1.17
acyl-lysine deacylase
|
–
|
|
|
BRENDA:
BS116207
|
|
|
|
nicotinic_acid_methyl_ester + H2O <=> nicotinate + methanol
|
3.5.1.19
nicotinamidase
|
–
|
|
|
BRENDA:
BS433926
|
|
|
|
p-Cresol + nicotinic_acid_mononucleotide <=> nicotinate + 4-hydroxyphenyl_alpha-D-ribose_5-phosphate
|
2.4.2.21
nicotinate-nucleotide---dimethylbenzimidazole phosphoribosyltransferase
|
–
|
|
|
BRENDA:
BS423928
|
|
|
|
nicotinic_acid_mononucleotide + 5-hydroxybenzimidazole <=> nicotinate + N1-(5-phospho-alpha-D-ribosyl)-5-hydroxybenzimidazole
|
2.4.2.21
nicotinate-nucleotide---dimethylbenzimidazole phosphoribosyltransferase
|
–
|
|
|
BRENDA:
BS435356
|
|
|
|
3-chloropyridine + H2O2 <=> 3-chloropyridine_N-oxide + 3-Pyridylcarbinol + Pyridine-3-aldehyde + nicotinate + H2O
|
1.11.2.1
unspecific peroxygenase
|
–
|
|
|
BRENDA:
BS414030
|
|
|
|
nicotinate + H2O + electron_acceptor <=> 6-Hydroxynicotinate + reduced_electron_acceptor
|
1.17.1.5
nicotinate dehydrogenase
|
–
|
|
|
BRENDA:
BS359203
|
|
|
|
nicotinic_acid_mononucleotide + adenine <=> 7-alpha-D-ribofuranosyladenine_5''-phosphate + nicotinate
|
2.4.2.21
nicotinate-nucleotide---dimethylbenzimidazole phosphoribosyltransferase
|
–
|
|
|
BRENDA:
BS323222
|
|
|
|
nicotinic_acid_mononucleotide + 5-nitrobenzimidazole <=> nicotinate + N1-(5-phospho-alpha-D-ribosyl)-5(6)-nitrobenzimidazole
|
2.4.2.21
nicotinate-nucleotide---dimethylbenzimidazole phosphoribosyltransferase
|
–
|
|
|
BRENDA:
BS323211
|
|
|
|
nicotinic_acid_mononucleotide + 5,6-dichlorobenzimidazole <=> nicotinate + N1-(5-phospho-alpha-D-ribosyl)-5,6-dichlorobenzimidazole
|
2.4.2.21
nicotinate-nucleotide---dimethylbenzimidazole phosphoribosyltransferase
|
–
|
|
|
BRENDA:
BS323210
|
|
|
|
nicotinic_acid_N-oxide + ferricytochrome_b5 + H+ <=> nicotinate + ferricytochrome_b5 + H2O
|
1.7.2.3
trimethylamine-N-oxide reductase
|
–
|
|
|
BRENDA:
BS287644
|
|
|
|
nicotinate + H2O + phenazine_methosulfate <=> 6-Hydroxynicotinate + reduced_phenazine_methosulfate
|
1.17.1.5
nicotinate dehydrogenase
|
–
|
|
|
BRENDA:
BS406114
|
|
|
|
ATP + nicotinate + CoA <=> AMP + diphosphate + nicotinyl-CoA
|
6.2.1.25
benzoate---CoA ligase
|
–
|
|
|
BRENDA:
BS258
|
|